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PROJECTS (2005 - 2006)

Peer Reviewed External Grants and Contracts


CARDIOLOGY

Principle Investigator

Project

Funding Agency

Basta, Magdy

Evaluation of Resynchronization Therapy for Heart Failure

St. Jude Medical

Basta, Magdy

Tolerance and Efficacy Study of RSD1235

Fujisawa

Basta, Magdy

Canadian Atrial Fibrillation Evaluation Study

Guidant Canada

Basta, Magdy

Canadian Registry Of ICD Implant Testing Procedures

Guidant Canada

Basta, Magdy

Lead LIFE study-Longterm Integrity Followup Evaluation

Guidant Canada

Bata, Iqbal

The WEST Study

Canadian Vigour Centre

Bata, Iqbal

Early Glycoprotein IIb/iia Inhibition

Millennium Pharmaceuticals

Bata, Iqbal

Ongoing Telmisartan Alone and in Combination with Ramipril Global Endpoint Trial

Hamilton Health Sciences Corporation

Bata, Iqbal

Focus on Coronary Unstable Syndromes

Aventis Pharma

Bata, Iqbal

Tilarginine Acetate Injection Study

Actelion Pharmaceuticals

Cox, Jafna

Global Risk Factor Assessment and Management Primary Prevention Initiative

Pfizer Canada

Cox, Jafna

A Novel Approach to Cardiovascular Health by Optimizing Risk Management

Pfizer Canada

Cox, Jafna

Pilot Study on the Efficacy of a specialized Thrombosis clinic

Dupont

Cox, Jafna

CCORT Project #5 Physician Perceptions Concerning Barriers to Complying with Quality Indicators Evaluated in Cardiac Report Cards

CIHR

Cox, Jafna

Improving Cardiovascular Outcomes in Nova Scotia

Merck

Crowell, Richard

Evaluation Of The Anti-anginal Efficacy And Safety Or Oral Administration Of Ivabradine

Servier Canada

Horacek, Milan

 

Phillips Medical System

Howlett, Jonathan

A Strategy of Telehome Care for Management of Congestive Heart Failure

Cardiome Pharma

Howlett, Jonathan

Surgical Treatment for Ischemic Heart Failure Trial

Astra Zeneca

Howlett, Jonathan

HF-Action-for Heart Failure and A Controlled Trial Investigating Outcomes of Exercise Training

National Institute of Health

Howlett, Jonathan

Study of a 2000mg Oral Dose of PG-116800 Given as the Sodium Salt (PG-530742) Twice Daily for 90 Days

National Heart, Lung & Blood Institute

Howlett, Jonathan

Follow-up Serial Infusion of Natrecor

Procter & Gamble

Howlett, Jonathan

Trial Evaluating the Role of Growth Hormone Therapy Compared to Standard Care

Novartis

Howlett, Jonathan

Dose Escalation Evaluation of the Pharmacokinetic and Hemodynamic Effects of Carperitide

Canadian Cardiovascular Collaboration

Love, Michael

Primary PCI Program

Ottawa Heart Institute Research Corporation

Love, Michael

A Study to evaluate the effect of Rosuvastatin on intravascular ultrasound-derived coronary atheroma burden

Eli Lilly

Quraishi, Ata

A Comparison Of CS-747 And Clopidogrel

St. Jude Medical

Quraishi, Ata

Safety and Efficacy of Enoxaparin in PCI Patients

Eli Lilly Canada

Rajda, Miroslaw

N-Terminal Pro-Brain Peptide for the Diagnosis of Heart Failure and the Prediction of Clinical Outcomes

Aventis

Rajda, Miroslaw

Study Evaluating The Overall Efficacy And Safety Including The Effect On Renal Function Of Sirolimus

Roche Diagnostics Canada

Rajda, Miroslaw

BEAUTIFUL Study

Hoffman LaRoche

Sapp, John

RAFT Study

Servier

Sapp, John

ACTIVE Study

CIHR

Sapp, John

Study Evaluating the Value of a Therapeutic Strategy to Restore and Maintain Simus Rhythm

Sanofi Synthelabo

Sapp, John

The Electrode Configuration Study

CIHR

Sapp, John

 

HSFNS

Sapp, John

 

Biosense Webster

Title, Lawrence

Evaluation of the Fixed Combination Torcetrapib/Atorvastatin, Administered Orally QD, Compared with Atorvastatin Alone

Guidant Canada

Title, Lawrence

COURAGE Trial

Pfizer

Title, Lawrence

Vein-Coronary Atherosclerosis and Rosiglitazone After Bypass Surgery Trial

Veterans Affairs

Title, Lawrence

ERASE Trial

GlaxoSmithKline

Title, Lawrence

AIM-HIGH Trial

CSL Limited

Title, Lawrence

Effect of Glucose Loading with or without Antioxidant Vitamins on Endothelial Function –D Glucose

National Heart, Lung & Blood Institute

Title, Lawrence

Coronary Artery Intravascular Ultrasound Evaluation of the Anti-Atherosclerotic Efficacy, Safety, and Tolerability of Fixed Combination CP-529,414/Atorvastatin Alone

AtheroGenics

Title, Lawrence

Ischemia Management with Accupril post Bypass Graft via. Inhibition of Converting Enzyme

Pfizer Canada

Title, Lawrence

Occulded Artery Trial & Total Occlusion Study of Canada

Parke Davis

Title, Lawrence

HOPE TOO

National Heart, Lung & Blood Institute

Title, Lawrence

Firefighters and Their Endothelium

MRC

Title, Lawrence

Study of the Sirolimus-Coated By Velocity Balloon-Expandable Stent

CIHR

Title, Lawrence

Study of the Efficacy & Safety of Long Term Administration of Nateglinide and Balsartan

Cordis

Title, Lawrence

Reduction of Vascular Inflammation and Coronary Atherosclerosis with AGI-1067

Novartis

Townley, Richard

RESTOR-CHF Study

AtheroGenics



CRITICAL CARE

Principle Investigator

Project

Funding Agency

Hall , Richard

Study of E5564, A Lipid A Antagonist

Eisai Medical Research

Hall , Richard

Trial of Prophylactic Heparin in Patients who are Undergoing Treatment with Drotrecogin Alfa (Activated)

Eli Lilly Canada

Hall , Richard

Study of the Safety and LIPOS Study

GlaxoSmithKline

Hall , Richard

 

Tanox

Hall , Richard

VALID Study

ALTANA Pharma



DERMATOLOGY

Principle Investigator

Project

Funding Agency

Langley, Richard

The Use of Kineret in the Treatment of FCU

Atlantic Provinces Dermatology Association



ENDOCRINOLOGY

Principle Investigator

Project

Funding Agency

Kaiser, Stephanie

Canadian Multicentre Osteoporosis Study

Health Canada

Kaiser, Stephanie

An Evaluation to Compare Lipid lowering effects of rosuvastatin and atorvastain

Astra Zeneca

Kaiser, Stephanie

Study to Determine the Efficacy and Safety of Intravenous Zoledronic Acid 5 mg Annually Compared to Oral Alendronate 70 mg Weekly

Novartis

Kaiser, Stephanie

Compliance with and Acceptance of Teriparatide Pen Use

Eli Lilly Canada

Rowe, Richard

Diabetes Reduction with Ramipril & Rosiglitazone Medication

CIHR

Rowe, Richard

Efficacy and Safety of EXUBERA (Inhaled Insulin) Compared with Subcutaneous Human Insulin Therapy

Pfizer Canada

Rowe, Richard

Effects of Candesartan Cilexetil on Diabetic Retinopathy

Astra Zeneca

Ur, Ehud

ACCORD Study

National Heart, Lung & Blood Institute

Ur, Ehud

Primary Care Diabetes Case Management

GlaxoSmithKline

Ur, Ehud

Study of rimonabant 20mg once daily

Sanofi Synthelabo Canada

Ur, Ehud

Study to compare the durability of glucose lowering and preservation of pancreatic Beta-cell function of reosilitazone monotherapy compared to metformin or glyburide

SmithKline Beecham

Ur, Ehud

Selenium and Vitamin E Cancer Prevention Trial

Southwest Oncology Group

Ur, Ehud

Study to Evaluate the Effects of LANTUS (Insulin Glargine) Versus Standard Care and Omega-3 Fatty Acids vs. Placebo

Aventis Pharma

Ur, Ehud

A Study to Compare the Efficacy and Safety of Pegvisomant to that of Sandostatin LAR®

Pharmacia Canada

Ur, Ehud

The Long-term Safety And Tolerability Of Sandostatin LAR

Novartis

Ur, Ehud

Study of Weight Reducing Effect and Safety of SR141716

Sanofi Synthelabo

Ur, Ehud

Evaluation of the Efficacy, Safety, and Tolerability of Fixed Combination Torcetrapib, Atorvastatin Administered Orally, Once Daily for 18 Weeks

Pfizer Canada

Ur, Ehud

Study to Evaluate Treatment With A Combination of Pegvisomant Plus Sandostatin LAR, Pegvisomant (Alone) and Sandostatin LAR Alone

Pfizer

Ur, Ehud

Study to investigate efficacy, safety, tolerability and pharmacokinetics of the DPPIV inhibitor RO0730699

Hoffman LaRoche

Ur, Ehud

Efficacy, Safety, and Tolerability of Fixed Combination Torcetrapid (CP-529,414)/Atorvastatin, Compared with Atorvastatin Therapy Alone, and Fenofibrate Alone

Pfizer Canada

Ur, Ehud

CanACTFAST Study

Pfizer Canada

Ur, Ehud

Trial of Blood Pressure Lowering with a Fixed Dose Low-Dose Perindopril-Inadapamide Combination and Intensive Glucose Control with a Modified Release Gliclazide Based Regimen

University of Montreal

Ur, Ehud

CAP Study

Pfizer Canada

Ur, Ehud

Study of Sandostatin LAR in the Therapy of Patients with Moderately Severe or Severe non-proliferative diabetic retinopathy or low risk proliferative diabetic retinopathy

Novartis

Ur, Ehud

Study of the efficacy and safety of long term administration of nateglinide and valsartan

Boehringer Ingelheim

Ur, Ehud

Trial Comparing Efficacy and Safety of Insulin Determir Versus Insulin Glargine

Novo Nordisk Canada

Ur, Ehud

Evaluation of Diabetic Retinopathy Progression

Aventis Pharma



GASTROENTEROLOGY

Principle Investigator

Project

Funding Agency

Farina, Dana

Study to Evaluate Different Dosing Regimens of Rabeprazole in Controlling Noctural Heartburn Symptoms

Janssen Ortho

Khaliq-Kareemi, Munaa

Safety Study to Assess the Safety of Chronic Therapy with the Humanised Anti-TNF PEG Conjugate CDP870 400mg sc

Celltech R&D Limited

Khaliq-Kareemi, Munaa

Study to Assess the Maintenance of Clinical Response to Humanised anti-TNF PEG Conjugate, CDP870 400 mg sc,

Celltech R&D Limited

Khaliq-Kareemi, Munaa

Study to Assess the Safety of Re-Exposure After a Variable Interval and Subsequent Chronic Therapy with the Humanised Anti-TNF PEG Conjugate CDP870 400mg sc

Celltech R&D Limited

Leddin, Desmond

MAGNETIC Healing of Patients After Treatment with Pantoprazole-Magnesium Dihydrate 80 mg o.d. in Comparison to Pantoprazole-Sodium Sesquilhydrate 40 mg o.d.

ALTANA Pharma

Leddin, Desmond

Study to Determine the Efficacy and Safety of VSL#3 Probiotic Food Supplement Mixture

Crohn’s & Colitis Found. Of Canada

Leddin, Desmond

Study to Evaluate Efficacy and Safety of Talnetant

GlaxoSmithKline

Leddin, Desmond

Study of Antibiotic Associated G.I. Side-Effects

Eli Lilly

Love, Jonathan

Safety and Efficacy of ALX-0600

Allelix

Love, Jonathan

A Pilot Study of the Safety and Efficacy of ALX-0600

Allelix

MacIntosh, Donald

Study of the Human Anti-TNF Monoclonal Antibody Adalimumab

Abbott Laboratories

MacIntosh, Donald

Study of the Safety and Efficacy of Intravenous Antegren

Elan Pharmaceuticals

MacIntosh, Donald

Study of the Safety, Tolerability, and Efficacy of intravenous Antegren

Elan Phamaceuticals and Abbott Laboratories

MacIntosh, Donald

Incidence of Post-ERCP pacreatitus in patients undergoing hydrophilic guide wire cannulation of the common bile duct versus standard cannulation with dye injection

Boston Scientific Corporation

MacIntosh, Donald

Study to Assess the Efficacy and Safety of Omega-3 Fatty Acids

John P. Robarts Research Institute

Peltekian, Kevork

Peg-INTRON Plus REBETOL

Schering Canada

Peltekian, Kevork

Study To Explore The Benefit Of A Conversion From Twice A Day Administration Of Neoral To A Once A Day Administration And To Identify The C2 Ranges

Novartis

Peltekian, Kevork

Study To Evaluate The Safety And Efficacy Of Celgosivir In Combination With Peginterferon Alfa-2b, With And Without Ribavirin For 12 Weeks

Migenix Inc

Peltekian, Kevork

Study To Evaluate The Efficacy And Safety Of Albuferon In Combination With Ribavirin

Human Resources Development Canada

Peltekian, Kevork

An Extension Protocol to Evaluate the Long Term Effects of Treatment with Peginterferon Alfa 2a or Roferon-A

Hoffman LaRoche

Peltekian, Kevork

PEG-Intro Maintenance Therapy vs. an Untreated Control Group for Prevention of Progression of Fibrosis

Schering Canada

Phalen-Kelly, Kelly

Will Disease Specific Teaching by an ERN Increase Patient Knowledge as Measure by the Crohn’s and Colitis Knowledge Score?

Nursing

Peterson, Theresa

 

CIHR

Turnbull, G.K.

Study to Evaluate the Safety, Tolerability, Pharmacodynamics and Pharmacokinetics of Multiple Doses and Dose Levels of DDP225

Dynogen Pharmaceuticals, Inc.

Turnbull, G.K.

Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of Multiple Doses and Dose Levels of DDP733

Dynogen Pharmaceuticals, Inc.

van Zanten, Sander

A Prospective Study On The Use Of And Indications For Treatment With H2-Blcokers And Proton Pump Inhibitors In Nova Scotia

Janssen Ortho and Canadian Digestive Health Foundation

van Zanten, Sander

HEARD Study

Astra Zeneca

van Zanten, Sander

Association Between Proton Pump Inhibitors Or H2 Blockers Program

Green Shield Canada

van Zanten, Sander

Study To Validate The Reflux Disease Questionnaire

Astra Zeneca

van Zanten, Sander

Study, to Assess the Efficacy and Safety of Tegaserod (6mg BID) and Placebo

Novartis

van Zanten, Sander

Study for up to 8 Weeks Treatment with AZD0865 25, 50, 75 mg and Esomeprazole 40 mg, Given Orally Once Daily

Astra Zeneca

van Zanten, Sander

Registry of Patients Undergoing Endoscopic and/or Acid Suppression Therapy and An Outcomes Analysis

Astra Zeneca

van Zanten, Sander

A retrospective review to assess the utilization of intravenous and oral proton pump inhibitors and histamine H2-receptor antagonists in Canadian hospitals

Astra Zeneca

van Zanten, Sander

 

CIHR



GENERAL MEDICINE

Principle Investigator

Project

Funding Agency

Pollak, PT

 

CIHR

Pollak, PT

 

NSHRF

Pollack, PT

 

HSFNS



GERIATRIC MEDICINE

Principle Investigator

Project

Funding Agency

MacKnight, Chris

Study Examining the Efficacy and Safety of Memantine on Behavioural Symptoms

Lundbeck Canada

MacKnight, Chris

Study Of VP4896 For The Treatment Of Mild-to-Moderate Alzheimer’s Disease

Voyager Pharmaceutical

MacKnight, Chris

Study of the Efficacy and Safety of Alzhemed

Neurochem

MacKnight, Chris

CIHR Special Recognition Award

CIHR

MacKnight, Chris

Study of the Efficacy and Safety of Atorvastatin 80 mg plus an Acetylcholinesterase Inhibitor vs an Acetylcholinesterase Inhibitor Alone

Pfizer Canada

MacKnight, Chris

Canadian Alzheimer’s Disease Quality Of Life Study

CIHR

MacKnight, Chris

Study of the Effect of Daily Treatment with MPC-7869 on Measures of Cognitive and Global Function

Myriad Pharmaceuticals

MacKnight, Chris

 

CIHR

MacPherson, Kathleen

Medications and Cognition

Merck Frosst Canada

Rockwood, Ken

Qualitative Analysis of Galantamine CIBIC Data

Janssen Ortho

Rockwood, Ken

VISTAR Study

Janssen Ortho

Rockwood, Ken

A New Initiative in Knowledge Transfer for the Management of Frailty

Merck Frosst Canada

Rockwood, Ken

Primary Pharmacologic Prevention of Alzheimer’s Disease

Merck Frosst Canada

Rockwood, Ken

Alzheimer Research

Merck

Rockwood, Ken

 

CIHR

Rockwood, Ken

 

Alzheimer Society of Canada

Rockwood, Ken

 

University of British Columbia



HEMATOLOGY

Principle Investigator

Project

Funding Agency

Anderson, David

The Van Gogh-DVT Trial

Sanofi Synthelabo

Anderson, David

Blood Surveillance Program

Department of Health

Anderson, David

Study Comparing the Efficacy and Safety of Once-Weekly Subcutaneous SanOrg34006 with the combination of Heparin and Vitamin K antagonist

Sanofi Synthelabo

Anderson, David

REVERSE Study

CIHR

Anderson, David

The SOX Trial

CIHR

Anderson, David

EINSTEIN Study

Bayer AG

Anderson, David

Study to investigate the efficacy, safety, tolerability, pharmacokinetics and pharmacodynamics of SB 497115-GR

GlaxoSmithKline

Couban, Stephen

Trial Comparing Early High Dose Chemoradiotherapy and an Autologous Stem Cell Transplant to Conventional Dose CHOP Chemotheraphy

National Cancer Institute of Canada

Couban, Stephen

Study of Gemcitabine, Dexmethasone, and Cisplantin Compared with Dexamethasone, Cytarabine, and Cisplatin

National Cancer Institute of Canada

Couban, Stephen

Trial of 3-weekly rhuMAb 2H7

Hoffmann La Roche

Couban, Stephen

Study of STI571 vs. Interferon-a Combined with Cytarabine

Novartis

Couban, Stephen

GLEEM Study

Novartis

Couban, Stephen

BEXXAR Study

3M Pharmaceuticals

Couban, Stephen

Study of Novel Erythropoiesis Stimulating Protein

Amgen Canada

Fernandez, L.A.

Study to Evaluate the Efficacy and Safety of Rituximab Plus Fludarabine and Cyclophosphamide vs. Fludarabine and Cyclophosphamide Alone

Hoffmann La Roche

Forrest, Donna

Trial Comparing CVP + MabThera to Standard CVP chemotherapy

Hoffman LaRoche

McCarron, Bonnie

Study on Extended BTE Prophylaxis

Aventis Pharma

McCarron, Bonnie

Trial of Prophylactic Low Molecular Weight Heparin

Ottawa Hospital

McCarron, Bonnie

Study of Central Venous Catheter Survival in Cancer Patients Using Low Molecular Weight Heparin

Pharmacia Canada

Pleasance, Susan

Quality End Of Life Care For Patients With Advanced Hematological Disorders And Their Caregivers

CIHR

Robinson, K. Sue

Trial of ABVD Versus Stanford V+-Radiation therapy

National Cancer Institute of Canada

Robinson, K. Sue

Trial Of Decitabine Versus Patient’s Choice With Physician Advice Of Either Supportive Care Or Low-Dose Cytarabine

MGI Pharma, Inc

Robinson, K. Sue

Study To Investigate The Safety And Efficacy Of Treanda TM

Salmedix

Robinson, K. Sue

Study of CLORETAZINE and Cytosine Arabinoside

ICI Pharma ( Canada)

Robinson, K. Sue

Study to Investigate the safety and Activity of SDX-105 in Combination with Rituximab

Salmedix

White, Darrell

Study of Thalidomide and Prednisone vs. No Further Therapy as Maintenance Following Autologous Stem Cell Transplant

National Cancer Institute of Canada

White, Darrell

Revimid Extension.

Celgene Corporation

White, Darrell

Study of Combination Thalidomide Plus Dexamethasone Therapy Versus Dexamethasone Therapy Alone

Celgene Corporation

White, Darrell

Study of Tositumomab and Iodine 131-Tosituomab

GlaxoSmithKline

White, Darrell

Protocol to provide Expanded Access to VELCADE

Ortho Biotech

White, Darrell

Study of PS-341 in Patients with Untreated or Relapsed Waldenström’s Macroglobulinemia

National Cancer Institute of Canada



INFECTIOUS DISEASES

Principle Investigator

Project

Funding Agency

Garduno, Rafael

 

NSERC

Haase, David

HIV Clinical Trials Network

Canadian HIV Trials Network

Haase, David

Determinants of Risk for Genital Chlamydia Infection in Canadian Street Youth

Health Canada

Haase, David

Comparative Trial of a Novel CCR5 Antagonist, UK 427,857 in Combination with Zidovudine/Lamivudine Versus Efavirenz in Combination with Zidovudine/Lamivudine

Pfizer

Hatchette, Todd

Diagnosis and Outcome of Q-Fever Community Acquired Pneumonia

University of Alberta

Johnston, Lynn

Study of Subcutaneous Recombinant IL-2 in Patients with HIV-1 Infection and CD4 Cell counts>=350 mm3

Canadian HIV Trials Network

Johnston, Lynn

Comparative safety and efficacy study of Tipranavir boosted with low dose Ritonavir vs. genotypically defined Protease Inhibitior/Ritonavir

Boehringer Ingelheim

Johnston, Lynn

Study of GT267-004 vs. Vancomycin, and GT267-004 vs. metrondinazole

PPD Canada

McNeil, Shelly

Study to Evaluate the Efficacy and Safety of Micafungin vs. Liposomal Amphotericin B

Fujisawa Canada

McNeil, Shelly

Comparative Study of Micafungin vs. Caspofungin As Antifungal Treatment

Fujisawa Canada

Schlech, Walter

Population-based Survey of Febrile Gastroenteritis due to Listeria Monocytogenes in Nova Scotia

ILSI North America

Schlech, Walter

SMART Study

Canadian HIV Trials Network

Schlech, Walter

Assessing the Efficacy of Pneumococcal Vaccine in HIV Patients

Providence Health Care Society

Schlech, Walter

Trial to Determine the Optimal Management of Patients with HIV Infection for Whom First and Second-Line Highly Active Antiretroviral Therapy Has Failed

Canadian HIV Trials Network

Schlech, Walter

 

CIHR



MEDICAL ONCOLOGY

Principle Investigator

Project

Funding Agency

Colwell, Bruce

Study of Intermittent Oral Cepecitabine with IV Oxaliplatin vs. Bolus and Continuous Infusion Fluorouracil/Intravenous Leucovorin with Intravenous Oxaliplatin

Hoffmann La Roche

Colwell, Bruce

Study of Cetuximab and Best Supportive Care vs. Best Supportive Care

National Cancer Institute of Canada

Colwell, Bruce

Study of Intermittent Oral Capecitabine with IV Oxaliplatin vs. Fluorouracil/Leucovorin as Adjuvant Therapy

Hoffmann La Roche

Davis , Mary

Study of ZD1839 250 Mg and 500 Mg Versus Methotrexate

Astra Zeneca

Davis , Mary

Study to Compare the Efficacy and Safety of Two CC-5013 Dose Regimens

Celgene Corporation

Davis , Mary

Study of BLP25 Liposome Vaccine

Biomira Ivc.

Dorreen, Mark

Study of Adjuvant STI571 Versus Placebo

National Cancer Institute of Canada

Gallant, Julie

A Pilot Project to Improve the Computer Database booking for Mammography services in Nova Scotia and Encourage preliminary database linkage of Gynecological and Breast Screening Services

Health Infrastructure Support program

Morzycki, Wojciech

Study of ZD1839 (250mg Tablet) Plus Best Supportive Care vs. Placebo Plus Best Supportive Care

Astra Zeneca

Morzycki, Wojciech

Trial Comparing Targretin Capsules/Cisplatin/Vinorelbine Versus Cisplatin/Vinorelbine

Ligand Pharmaceuticals

Rayson, Daniel

Trial In Pancreatic Cancer Comparing (1) 5FU and D-L Folinic Acid vs. (2) Gemcitabine vs. (3) No Adjuvant Treatment

National Cancer Institute of Canada

Rayson, Daniel

Trial of Caelyx and Cyclophosphamide

Schering Canada

Rayson, Daniel

 

CARE

Reyno, L.

Trial of Sequenced EC + Filgrastim + Epoetin Alfa Followed by Paclitaxel vs. CEC as Therapy

National Cancer Institute of Canada

Reyno, L.

Randomized Trial of Epoetin Alfa

Ontario Clinical Oncology Group

Skillings, J.

A 28 day Oral Regimen of 5-Fluorouracil + 776C85 vs. Intravenous 5-Fluorouracil + Leucovorin as First-line therapy

Glaxo

Wood , Lori

Study of Interferon Alfa Alone, CCI-779 Alone, and the Combination of Interferon Alfa and CCI-779

Wyeth Research

Wood , Lori

A SU011248 Treatment Protocol For Patients With Cytokine-Refarctory Metastatic Renal Carcinoma

Pfizer

Wood , Lori

Study Evaluating the Efficacy and Safety of ABT-751

Abbott Laboratories

Wood , Lori

Study Evaluating the Safety and Efficacy of ABT-510

Abbott Laboratories

Wood , Lori

Trial of Interferon Alfa-2B or Interferon Alfa-2B Plus Bevacibumab

Cancer Trials Support Unit

Wood, Lori

 

CARE

Wood, Lori

 

Cancer Care Nova Scotia



NEPHROLOGY

Principle Investigator

Project

Funding Agency

Keough-Ryan, Tammy

Study to Evaluate the Efficacy and Safety of High Doses of Candesartan Cilexetil on the Reduction of Proteinuria

Astra Zeneca

Kiberd, Bryce

Study comparing CellCept administered as a component of tacrolimus based immunosuppression therapy

Hoffmann La Roche

Kiberd, Bryce

Cardiac Risk Reduction in the Kidney Transplant Clinic

Fujisawa Canada

Soroka, Steven

Canadian Prevention of Renal and Vascular Endpoints Trial

CIHR

Soroka, Steven

Study to Demonstrate the Efficacy and Safety of RO0503821 when Administered Intravenously

Hoffman LaRoche

Soroka, Steven

Study Evaluating Once Monthly Darbepoetin Alfa Dosing

Amgen Canada

Soroka, Steven

Chronic Kidney Disease Project

Baxter Healthcare Corporation

Soroka, Steven

A study to evaluate the use of Rosuvastatin in subjects on regular haemodialysis

Astra Zeneca

Soroka, Steven

An Active Safety Surveillance Plan to Conduct Serologic Testing for Anti-Erythropoietin Antibodies and Prospectively Monitor the Incidence of Pure Red Cell Aplasia (PRCA)

Ortho Biotech

Soroka, Steven

Treatment Trial to Compare MICARDIS® 80mg vs. COZAAR® 100mg

Boehringer Ingelheim

Soroka, Steven

Oral Calcimimtic Agent When Two Different Vitamin C Regimens are Used

Amgen

Soroka, Steven

Trial to Reduce Cardiovascular Events with Aranesp Therapy

Amgen Canada

Storsley, Leroy

The Long-Term Medical And Psychosocial Implications Of Becoming A Living Kidney Donor

Canadian Institutes of Health Research

West, Ken

 

CIHR

West, Ken

 

CARE

West, Ken

 

Kidney Foundation

West, Michael

Pharmacokinetic/Pharmacodynamic Study of Replagal

Transkaryotic Therapies

West, Michael

Study of the Safety and Efficacy of Fabrazyme

Genzyme Corporation

West, Michael

Registry of Fabry Disease

Transkaryotic Therapies



NEUROLOGY

Principle Investigator

Project

Funding Agency

Benstead, Timothy

Treatment for Peripheral Neuropathy

Eli Lilly Canada

Benstead, Timothy

Treatment for Symptomatic Peripheral Neuropathy

Eli Lilly Canada

Bhan, Virender

Study to Evaluate the Safety, Tolerability and Efficacy of NBI-5788

Neurocrine Biosciences

Bhan, Virender

BEYOND Study

Berlex Canada

Bhan, Virender

Study to Evaluate the Efficacy and Safety of Teriflunomide in Reducing the Frequency of Relapses and Delaying the Accumulation of Physical Disability

Aventis Pharma

Bhan, Virender

ACHIEVE Study

Teva Neuroscience

Bhan, Virender

Study to Evaluate the Safety and Efficacy of Rituximab

Genentech

Bhan, Virender

Study of a Serum-Free Pre-Formulated Solution of AVONEX (Administered Intramuscularly

Biogen

Bhan, Virender

Paediatric Demyelination Study

Multiple Sclerosis Society of Canada

Bhan, Virender

Prospective Study Of The Clinical Epidemiology, Pathobiology, And Neuroimaging Features Of Canadian Children With Clinically Isolated Demyelinating Syndromes

Multiple Sclerosis Society of Canada

Bhan, Virender

Dose Finding, Safety, Tolerability, and Efficacy Study of the Active Extension Phase

Abbott Laboratories

Darvesh, Sultan

 

CIHR

Darvesh, Sultan

 

NSHRF

Darvesh, Sultan

 

HSFC

Darvesh, Sultan

 

Alzheimer Society of Canada

Darvesh, Sultan

 

Brain Tumor Foundation

Grant, Ian

Study of the Efficacy and Safety of AS-3201

Dainippon

Grant, Ian

Comparative Study of the Effect of Riluzole 50 mg bid on the Survival of ALS Subjects Compared to Historical Controls

Aventis Pharma

Gubitz, Gordon

Study of Secondary Prevention of Small Subcortical Strokes

National Institute of Health

Gubitz, Gordon

Confirmatory Efficacy And Safety Trial Of Activated Recombinant Factor VII

Novo Nordisk Canada

Kirby, Sarah

Study of IV Edotecarin vs Temozolomide or Carmustine or Lomustine

Pfizer Canada

Murray, T. J.

The Canadian Collaborative Project on Genetic Susceptibility to Multiple Sclerosis

Multiple Sclerosis Society of Canada

Murray, T. J.

Controlled High Risk AVONEX MS Prevention Study

Biogen

Murray, T. J.

Observational Study of Treatment with Betaseron for Early-Stage Relapsing-Remitting Multiple Sclerosis

Berlex Canada

Murray, T. J.

Study to Determine the Safety & Efficacy of Natalizumab

Biogen

Murray , T.J.

 

Music in Medicine

Murray , T.J.

 

NSHRF

Phillips, Stephen

Stroke Audit

Department of Health

Phillips, Stephen

Study to Assess the Efficacy and Safety of Intravenous NXY-059 in Acute Ischemic Stroke

Astra Zeneca

Phillips, Stephen

Registry of the Canadian Stroke Network

Canadian Stroke Network

Phillips, Stephen

CHARISMA Trial

Sanofi Synthelabo Canada

Phillips, Stephen

Cerebral Hemorrhage and NXY Treatment Study to Assess the Safety and Tolerability of 72 Hours IV Infusion of NXY-059

Astra Zeneca

Phillips, Stephen

The Economic Burden Of Ischemic Stroke In Canada

Sunnybrook & Women’s College Health Sciences Centre

Phillips, Stephen

Study of the Efficacy and Safety of I.V. Clomethizole Compared to Placebo

Astra

Purdy, Allan

Study To Assess the Efficacy, Tolerability and Safety of Oral Frovatriptan

Vernalis Development

Purdy, Allan

Clinical Study Of Migraine Evolution

GlaxoSmithKline

Sadler, Mark

Pregabalin BID Add-On Trial

Pfizer Canada

Sadler, Mark

Study to Evaluate the Efficacy and Safety of Adjunctive Treatment with 3000 mg/day oral Levetiracetam

Parexel

Weaver, Donald

 

NSERC

Weaver, Donald

 

Alzheimer Society of Canada

Weaver, Donald

 

NSHRF

Weaver, Donald

 

CIHR

Weaver, Donald

 

CFI

Weaver, Donald

 

AIF



PHYSICAL MEDICINE & REHABILITATION

Principle Investigator

Project

Funding Agency

Kirby, Lee

 

CIHR

Kirby, Lee

 

CIHR

Kirby, Lee

 

CIHR

Short, Christine

Study to Evaluate Safety, Tolerability and Activity of Oral Fampridine-SR

Acorda Therapeutics

Short, Christine

Study to Evaluate Safety and Efficacy of Oral Fampridine-SR (10mg B.I.D.) in Subjects with Multiple Sclerosis

Acorda Therapeutics



RESPIROLOGY

Principle Investigator

Project

Funding Agency

Hernandez, Paul

Effects of Home-Based versus Hospital-Based Outpatient Pulmonary Rehabilitation in Patients with COPD

CIHR

Hernandez, Paul

Measurement of Exertional Dyspnea in the Clinical Setting in Patients with COPD

Boehringer Ingleheim

Hernandez, Paul

Trial to Evaluate the Effect of Tiotropium Inhalation Capsules on the Magnitude of Exercise

Boehringer Ingelheim

Hernandez, Paul

Efficacy and safety comparison of one year treatment of two doses (5ug (2 actuations of 2.5 ug) and 10ug (2 acutations of 5ug) of Tiotropium Inhalation Solution

Boehringer Ingelheim

Hernandez, Paul

Study Of The Phosphodiesterase Type 5 Inhibitor Tadalafil

Lilly ICOS LLC

Hernandez, Paul

Comparison of Treatment with ARIFLO to that of Placebo for Changes in Ventilatory Mechanics and Function

GlaxoSmithKline

Hernandez, Paul

Asthma In Obese Subjects

CIHR

McIvor, Andrew

Study to Investigate the Effect of 500 mcg Roflumilast Tablets o.d. vs. Placebo on Parameters Indicative of Hyperinflation

ALTANA Pharma

McIvor, Andrew

Optimal Therapy of COPD to Prevent Exacerbations and Improve Quality of Life

CIHR

McIvor, Andrew

Effect of Roflumilast on Exacerbation Rate

Altana Pharma Group

McIvor, Andrew

Study of the Safety and Efficacy of Interferon gamma1b

Intermune Inc

McIvor, Andrew

Study of the Efficacy & Safety of Tigecycline vs. Levofloxacin

Wyeth Research

Michael, R.

Trial Evaluating Aztreonam Lysinate for Inhalation in Cystic Fibrosis Patients

Corus Pharma, Inc.

Michael, R.

Dose Response Study to Determine the Optimum Dose of Dry Powder Mannitol Required to Generate Clinical Improvement

Pharmaxis Ltd



RHEUMATOLOGY

Principle Investigator

Project

Funding Agency

Hanly, John

Study of Neuropsychiatric Systemic Lupus Erythematosus

CIHR

Hanly, John

Study of the Human anti-TNF monoclonal antibody D2E7 in Rheumatoid Arthritis Patients

Knoll Pharma

Hanly, John

The Genes Study

CIHR

Hanly, John

Trial to assess the efficacy and safety of mycophenolate mofetil in inducing response and maintaining remission

Aspreva Pharmaceuticals

Hanly, John

 

CIHR

Sutton, Evelyn

Trial for Patients Completing Study M02-518 and M02-570 of the Human Anti-TNF Monoclonal Antibody Adalimumab

Abbott Laboratories